- Patent Title: Recombinant ROBO2 proteins, compositions, methods and uses thereof
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Application No.: US15995286Application Date: 2018-06-01
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Publication No.: US10906955B2Publication Date: 2021-02-02
- Inventor: Stephen Berasi , Janet Elizabeth Buhlmann , Nathan Higginson-Scott , Michael Shamashkin , Matthew Russo , Stefano V. Gulla , Zong Sean Juo , Sreekumar R. Kodangattil , Weining Lu , Xueping Fan , David J. Salant
- Applicant: Pfizer Inc. , Boston Medical Center Corporation
- Applicant Address: US NY New York; US MA Boston
- Assignee: Pfizer Inc.,Boston Medical Center Corporation
- Current Assignee: Pfizer Inc.,Boston Medical Center Corporation
- Current Assignee Address: US NY New York; US MA Boston
- Agency: Haley Guiliano LLP
- Agent James F. Haley, Jr.; Brian M. Gummow
- Main IPC: C07K14/705
- IPC: C07K14/705 ; C07K19/00 ; C12N15/09 ; C12N15/11 ; C12N15/52 ; C12N15/63 ; C07H21/04 ; A61P13/12 ; A61K38/17 ; A61K38/00
Abstract:
The invention provides recombinant Roundabout Receptor 2 (ROBO2) proteins designed to bind SLIT ligands and prevent their binding to ROBO2 cell surface receptors. Also provided are methods for use of these recombinant ROBO2 proteins.
Public/Granted literature
- US20180346542A1 RECOMBINANT ROBO2 PROTEINS, COMPOSITIONS, METHODS AND USES THEREOF Public/Granted day:2018-12-06
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