Invention Grant
- Patent Title: Methods of treating autoimmune disease or chronic inflammation wtih antibodies that bind peptidoglycan recognition protein 1
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Application No.: US16171131Application Date: 2018-10-25
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Publication No.: US10906965B2Publication Date: 2021-02-02
- Inventor: Vibeke Westphal Stennicke , Christine Brender Read , Joseph Leon Kuijper , Xiaoting Tang , Mark Heipel , Siv Annegrethe Hjorth
- Applicant: Novo Nordisk A/S
- Applicant Address: DK Bagsvaerd
- Assignee: Novo Nordisk A/S
- Current Assignee: Novo Nordisk A/S
- Current Assignee Address: DK Bagsvaerd
- Agency: Morgan, Lewis & Bockius LLP
- Priority: EP12158974 20120312
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/18
Abstract:
Disclosed herein is a method for identifying TREM-1's ligand and antibodies, or fragments thereof, which are capable of modifying the function of TREM-1's ligand. Antibodies that reduce or block TREM-1 activation may be identified and selected using this method. Antibodies that bind to TREM-1's ligand and reduce TREM-1 activity may be suitable for use as medicaments.
Public/Granted literature
- US20190119367A1 ANTIBODIES THAT BIND PEPTIDOGLYCAN RECOGNITION PROTEIN 1 Public/Granted day:2019-04-25
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