Invention Grant
- Patent Title: Local orbital therapy for thyroid eye disease
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Application No.: US16307411Application Date: 2017-06-08
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Publication No.: US10906969B2Publication Date: 2021-02-02
- Inventor: N. Grace Lee , Leo Kim , Patricia A. D'Amore , James A. Stefater
- Applicant: Massachusetts Eye and Ear Infirmary , Schepens Eye Research Institute
- Applicant Address: US MA Boston; US MA Boston
- Assignee: Massachusetts Eye and Ear Infirmary,Schepens Eye Research Institute
- Current Assignee: Massachusetts Eye and Ear Infirmary,Schepens Eye Research Institute
- Current Assignee Address: US MA Boston; US MA Boston
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2017/036517 WO 20170608
- International Announcement: WO2017/218284 WO 20171221
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/22 ; C07K16/20 ; A61K38/47 ; C07K14/475 ; C07K14/71 ; C07K16/28 ; A61K9/00 ; A61K9/08 ; A61K38/17 ; A61K38/00 ; A61K39/00
Abstract:
Methods of treating acute thyroid eye disease (TED) by administering a inhibitor, e.g., a VEGF-A inhibitor, e.g., an anti-VEGF antibody, optionally in combination with hyaluronidase, by periorbital or intraorbital injection. Also compositions comprising a VEGF inhibitor and hyaluronidase.
Public/Granted literature
- US20190276529A1 Local Orbital Therapy for Thyroid Eye Disease Public/Granted day:2019-09-12
Information query
