Invention Grant
- Patent Title: Anti-GPR20 antibody and anti-GPR20 antibody-drug conjugate
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Application No.: US16990330Application Date: 2020-08-11
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Publication No.: US10906974B2Publication Date: 2021-02-02
- Inventor: Kenji Iida , Takehiro Hirai , Tomoko Terauchi , Kensuke Nakamura
- Applicant: DAIICHI SANKYO COMPANY, LIMITED
- Applicant Address: JP Tokyo
- Assignee: DAIICHI SANKYO COMPANY, LIMITED
- Current Assignee: DAIICHI SANKYO COMPANY, LIMITED
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Priority: JP2017-006004 20170117
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K47/68 ; A61K31/4745 ; A61K47/64 ; A61K39/395 ; A61P35/00 ; A61K45/06 ; C12N15/09 ; C12N5/10 ; A61K39/00
Abstract:
It is an object of the present invention to provide an antibody specifically binding to GPR20-positive tumor cells such as GIST, a pharmaceutical product comprising the antibody and having therapeutic effects on a tumor, a method for treating a tumor using the aforementioned pharmaceutical product, and the like. It is another object of the present invention to provide an anti-GPR20 antibody having internalization activity, an antibody-drug conjugate containing the antibody, and the like.
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