Invention Grant
- Patent Title: Antisense antibacterial compounds and methods
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Application No.: US16064273Application Date: 2016-12-22
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Publication No.: US10907158B2Publication Date: 2021-02-02
- Inventor: David Greenberg , Bruce L. Geller , Erdal Toprak
- Applicant: Board of Regents, The University of Texas System , Oregon State University
- Applicant Address: US TX Austin; US OR Corvallis
- Assignee: Board of Regents, The University of Texas System,Oregon State University
- Current Assignee: Board of Regents, The University of Texas System,Oregon State University
- Current Assignee Address: US TX Austin; US OR Corvallis
- Agency: Parker Highlander PLLC
- International Application: PCT/US2016/068373 WO 20161222
- International Announcement: WO2017/112885 WO 20170629
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K47/64 ; A61K31/713 ; A61P31/04 ; C07K4/02 ; C07K14/005 ; C12N9/12
Abstract:
Provided are antisense morpholino oligomers targeted against bacterial virulence factors such as genes that contribute to antibiotic resistance or biofilm formation, or essential genes, and related compositions and methods of using the oligomers and compositions, for instance, in the treatment of an infected mammalian subject.
Public/Granted literature
- US20190078095A1 ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS Public/Granted day:2019-03-14
Information query
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