Invention Grant
- Patent Title: Compounds for improved viral transduction
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Application No.: US16665892Application Date: 2019-10-28
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Publication No.: US10907177B2Publication Date: 2021-02-02
- Inventor: Garrett Collins Heffner , Abraham Isaac Bassan
- Applicant: bluebird bio, Inc.
- Applicant Address: US MA Cambridge
- Assignee: bluebird bio, Inc.
- Current Assignee: bluebird bio, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Morse, Barnes-Brown & Pendleton, P.C.
- Agent Lisa M. Warren, Esq.
- Main IPC: C12N15/86
- IPC: C12N15/86 ; C12N5/0789 ; A61K38/46 ; C12N15/867 ; A61K35/12
Abstract:
The present invention provides methods and compositions for improving efficacy of viral transduction of cells. More particularly, the present invention provides methods and materials useful for safely and reliably improving the efficiency of methods and materials useful for safely and reliably improving the efficiency of methods for transducing cells, such as human hematopoietic stem cells (HSC), with viruses and/or viral vectors. The compositions and methods are useful for therapeutic indications amenable to treatment with hematopoietic stem cell gene therapies.
Public/Granted literature
- US20200048657A1 COMPOUNDS FOR IMPROVED VIRAL TRANSDUCTION Public/Granted day:2020-02-13
Information query
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