Invention Grant
- Patent Title: Extracellular production of designer hydroxyalkanoyloxy alkanoic acids with recombinant bacteria
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Application No.: US15742246Application Date: 2016-07-06
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Publication No.: US10907180B2Publication Date: 2021-02-02
- Inventor: Lars M. Blank , Till Tiso , Andrea Germer
- Applicant: Rheinisch-Westfaelische Technische Hochshule Aachen (RWTH)
- Applicant Address: DE Aachen
- Assignee: Rheinisch-Westfaelische Technische Hochshule Aachen (RWTH)
- Current Assignee: Rheinisch-Westfaelische Technische Hochshule Aachen (RWTH)
- Current Assignee Address: DE Aachen
- Agency: Kagan Binder, PLLC
- Priority: EP15175922 20150708
- International Application: PCT/IB2016/054037 WO 20160706
- International Announcement: WO2017/006252 WO 20170112
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12P7/62 ; C12P7/64 ; C12N9/10 ; C12P7/42

Abstract:
The present invention relates to a host cell comprising an rhlA gene or an ortholog thereof that is capable of producing hydroxyalkanoyloxy alkanoic acid (HAA) and achieving an HAA concentration of more than 1 g L−1 when cultured. The invention further relates to methods of producing such a host cell and to the use of said host cell for producing HAA. The present invention also relates to methods of producing HAA using said host cell, HAA compositions produced by these methods, as well as methods of producing fatty acid compositions, fatty alcohol compositions, or hydrocarbon compositions comprising producing HAA using said host cell, and fatty acid compositions, fatty alcohol compositions, or hydrocarbon compositions produced by said methods.
Public/Granted literature
- US20180112241A1 EXTRACELLULAR PRODUCTION OF DESIGNER HYDROXYALKANOYLOXY ALKANOIC ACIDS WITH RECOMBINANT BACTERIA Public/Granted day:2018-04-26
Information query
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