Invention Grant
- Patent Title: Overexpression of n-glycosylation pathway regulators to modulate glycosylation of recombinant proteins
-
Application No.: US16875832Application Date: 2020-05-15
-
Publication No.: US10907186B2Publication Date: 2021-02-02
- Inventor: Shivani Gupta , Sohye Kang
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agent Henry P. Wu
- Main IPC: C12N15/00
- IPC: C12N15/00 ; A61K38/00 ; C12P21/00 ; C12N9/10 ; C12N15/85 ; C07K14/705 ; C07K16/00
Abstract:
Methods of modulating the properties of a cell culture expressing a protein of interest are provided. In various embodiments the methods relate to the overexpression of proteins involved in the N-glycosylation pathway.
Public/Granted literature
- US20200277642A1 OVEREXPRESSION OF N-GLYCOSYLATION PATHWAY REGULATORS TO MODULATE GLYCOSYLATION OF RECOMBINANT PROTEINS Public/Granted day:2020-09-03
Information query
IPC分类:
