Invention Grant
- Patent Title: Combined immunoassay and magnetic immunoassay systems and devices for extended range of sensitivity
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Application No.: US15835972Application Date: 2017-12-08
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Publication No.: US10908154B2Publication Date: 2021-02-02
- Inventor: Jing Hua Hu , Antti Leo Oskari Virtanen , Cary James Miller , Kenneth Harold Hardage
- Applicant: Abbott Point of Care Inc.
- Applicant Address: US NJ Princeton
- Assignee: Abbott Point of Care Inc.
- Current Assignee: Abbott Point of Care Inc.
- Current Assignee Address: US NJ Princeton
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: G01N33/543
- IPC: G01N33/543 ; G01N33/549 ; G16H10/40 ; B01L3/00 ; C08L79/08 ; C01G53/00 ; C08L29/04 ; G01N27/327 ; C01F17/30

Abstract:
The present invention relates to systems that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device is provided for detecting an analyte in a biological sample. The device includes a first electrochemical sensor positioned on a substrate. The first electrochemical sensor includes an immobilized layer of antibody configured to bind to the analyte. The device further includes a second electrochemical sensor positioned adjacent to the first electrochemical sensor on the substrate, and a magnetic material that generates a magnetic field aligned with respect to the second electrochemical sensor. The magnetic field captures magnetic beads that have an immobilized layer of antibody configured to bind to the analyte, and concentrates the magnetic beads on or near a surface of the second electrochemical sensor.
Public/Granted literature
- US20180164303A1 COMBINED IMMUNOASSAY AND MAGNETIC IMMUNOASSAY SYSTEMS AND DEVICES FOR EXTENDED RANGE OF SENSITIVITY Public/Granted day:2018-06-14
Information query
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