Invention Grant
- Patent Title: Dual-column LC-MS system and methods of use thereof
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Application No.: US16260471Application Date: 2019-01-29
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Publication No.: US10908166B2Publication Date: 2021-02-02
- Inventor: Shunhai Wang
- Applicant: Regeneron Pharmaceuticals, Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Smith, Gambrell & Russell, LLP
- Main IPC: C07K1/16
- IPC: C07K1/16 ; G01N33/68 ; G01N30/46 ; B01J20/281 ; G01N30/72 ; B01D15/18 ; C07K1/20 ; G01N30/88
Abstract:
Methods for achieving complete sequence coverage of monoclonal antibodies by trypsin digestion and dual-column LC-MS system are provided. The disclosed method improves upon current techniques for standard peptide mapping.
Public/Granted literature
- US20190234960A1 DUAL-COLUMN LC-MS SYSTEM AND METHODS OF USE THEREOF Public/Granted day:2019-08-01
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