Invention Grant
- Patent Title: Method of fast imaging of NMR parameters with variably-accelerated sensitivity encoding
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Application No.: US16091785Application Date: 2017-04-07
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Publication No.: US10908235B2Publication Date: 2021-02-02
- Inventor: Yi Zhang , Jinyuan Zhou , Paul A. Bottomley
- Applicant: The Johns Hopkins University
- Applicant Address: US MD Baltimore
- Assignee: The Johns Hopkins University
- Current Assignee: The Johns Hopkins University
- Current Assignee Address: US MD Baltimore
- Agency: Venable LLP
- Agent Henry J. Daley
- International Application: PCT/US2017/026706 WO 20170407
- International Announcement: WO2017/177197 WO 20171012
- Main IPC: G01R33/24
- IPC: G01R33/24 ; G01R33/561 ; G01R33/48 ; G01R33/50 ; G01R33/56 ; G01R33/563

Abstract:
A method of spatially imaging a nuclear magnetic resonance (NMR)parameter whose measurement requires the acquisition of spatially localized NMR signals in a sample includes placing the sample in an MRI apparatus with a plurality of MRI detectors each having a spatial sensitivity map; and applying MRI sequences adjusted to be sensitive to the NMR parameter. At least one of the MRI sequences is adjusted so as to substantially fully sample an image k-space of the sample. The remainder of the MRI sequences is adjusted to under-sample the image k-space. The method further includes acquiring image k-space NMR signal datasets; estimating a sensitivity map of each of the MRI detectors using a strategy to suppress unfolding artefacts; and applying the estimated sensitivity maps to at least one of the image k-space NMR signal data sets to reconstruct a spatial image of NMR signals that are sensitive to the NMR parameter.
Public/Granted literature
- US20190101603A1 METHOD OF FAST IMAGING OF NMR PARAMETERS WITH VARIABLY-ACCELERATED SENSITIVITY ENCODING Public/Granted day:2019-04-04
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