Aspects of the technology described herein provide a personalized computing experience for a user based on a predicted future semantic location of the user. In particular, a likely future location (or sequences of future locations) for a user may be determined, including contextual information about the future location. Using information from the current context of the user's current location with historical observations about the user and expected user events, out-of-routine events, or other lasting or ephemeral information, a prediction of one or more future semantic locations and corresponding confidences may be determined and used for providing personalized computing services to the user. The prediction may be provided to an application or service such as a personal assistant service associated with the user, or may be provided as an API to facilitate consumption of the prediction information by an application or service.