Invention Grant
- Patent Title: Non-hormonal compositions and methods for male contraception
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Application No.: US16362081Application Date: 2019-03-22
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Publication No.: US10912762B2Publication Date: 2021-02-09
- Inventor: Guillaume El Glaoui , Mehdi El Glaoui , Philippe Perrin , Stéphane Droupy , Véronique Agathon-Meriau
- Applicant: LABORATOIRES MAJOR
- Applicant Address: FR Paris
- Assignee: LABORATOIRES MAJOR
- Current Assignee: LABORATOIRES MAJOR
- Current Assignee Address: FR Paris
- Agency: Nixon Peabody LLP
- Agent Mark J. FitzGerald
- Priority: EP18305328 20180323
- Main IPC: A61K31/4045
- IPC: A61K31/4045 ; A61P15/16 ; A61K9/16 ; A61K9/00 ; A61K9/50 ; A61K45/06

Abstract:
The present invention relates to non-hormonal compositions and methods for inducing a condition of aspermia, azoospermia, or severe oligozoospermia in the male subject such that these compositions and methods for administering the same may be used as male contraception. Embodiments of the present invention may comprise a composition comprising an alpha-1-adrenoreceptor antagonist, such as (R)-silodosin, for daily administration to a male subject. The compositions and related methods may further include pharmaceutically acceptable carriers. The present invention further includes formulations which allow for a delay such that delayed or missed dose(s) do not nullify the contraceptive effect of the treatment regimen. Such compositions and methods may also avoid the side effects associated with typical formulations of alpha-1-adrenoreceptor antagonists.
Public/Granted literature
- US20190290615A1 NON-HORMONAL COMPOSITIONS AND METHODS FOR MALE CONTRACEPTION Public/Granted day:2019-09-26
Information query
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