Invention Grant
![1-[(pyridin-3-yl-sulfonyl)-1H-pyrrol-3-yl] methanamine derivative and pharmaceutical composition and use thereof](/docs/US/2021-02-09/US10912769B2/abs.jpg.600x600.jpg)
- Patent Title: 1-[(pyridin-3-yl-sulfonyl)-1H-pyrrol-3-yl] methanamine derivative and pharmaceutical composition and use thereof
-
Application No.: US16337714Application Date: 2017-09-27
-
Publication No.: US10912769B2Publication Date: 2021-02-09
- Inventor: Zhongyi Geng , Xinghai Chen
- Applicant: Jiangsu Jibeier Pharmaceutical Co. Ltd. , Zhenjiang San An Pharmaceutical Co. Ltd.
- Applicant Address: CN Zhenjiang; CN Zhenjiang
- Assignee: Jiangsu Jibeier Pharmaceutical Co. Ltd.,Zhenjiang San An Pharmaceutical Co. Ltd.
- Current Assignee: Jiangsu Jibeier Pharmaceutical Co. Ltd.,Zhenjiang San An Pharmaceutical Co. Ltd.
- Current Assignee Address: CN Zhenjiang; CN Zhenjiang
- Agency: Fish & Richardson P.C.
- Priority: CN201610870802 20160929
- International Application: PCT/CN2017/103744 WO 20170927
- International Announcement: WO2018/059455 WO 20180405
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/4439 ; A61P1/04
![1-[(pyridin-3-yl-sulfonyl)-1H-pyrrol-3-yl] methanamine derivative and pharmaceutical composition and use thereof](/abs-image/US/2021/02/09/US10912769B2/abs.jpg.150x150.jpg)
Abstract:
Provided in the present invention are a 1-[(pyridin-3-yl-sulfonyl)-1h-pyrrol-3-yl] methanamine derivative having the structure shown below in formula (I) and a pharmaceutical composition and use thereof. The 1-[(pyridin-3-yl-sulfonyl)-1h-pyrrol-3-yl] methanamine derivative provided in the present invention has good gastric acid secretion inhibitory activities and excellent pharmacodynamic properties, while having relatively low toxicity.
Public/Granted literature
Information query
