Invention Grant
- Patent Title: Crystal form of orexin receptor antagonist compound, and preparation method and application thereof
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Application No.: US16864148Application Date: 2020-04-30
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Publication No.: US10912775B2Publication Date: 2021-02-09
- Inventor: Songliang Wu , Zhi Luo , Yuan Chen , Yuhe Wang , Dakun Qin , Xiaolin Li , Zheng Wang , Weidong Li , Haiying He
- Applicant: Shanghai Haiyan Pharmaceutical Technology Co., Ltd. , Yangtze River Pharmaceutical Group Co., Ltd.
- Applicant Address: CN Shanghai; CN Taizhou
- Assignee: Shanghai Haiyan Pharmaceutical Technology Co., Ltd.,Yangtze River Pharmaceutical Group Co., Ltd.
- Current Assignee: Shanghai Haiyan Pharmaceutical Technology Co., Ltd.,Yangtze River Pharmaceutical Group Co., Ltd.
- Current Assignee Address: CN Shanghai; CN Taizhou
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Agent Lars H. Genieser
- Priority: CN201510501331 20150814
- Main IPC: C07D451/02
- IPC: C07D451/02 ; A61K31/506 ; A61K31/46 ; A61P25/34 ; A61P25/20 ; A61P25/22 ; A61P11/08
Abstract:
Disclosed are a preparation method of an orexin receptor antagonist compound 5-3. Crystalline forms I-IV of an orexin receptor antagonist compound 5-3 are provided. Also provided are processes of preparing crystalline forms of the orexin receptor antagonist compound 5-3, as well as methods of using the crystalline forms I-IV for treating an orexin-related disease.
Public/Granted literature
- US20200261452A1 CRYSTAL FORM OF OREXIN RECEPTOR ANTAGONIST COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREOF Public/Granted day:2020-08-20
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