Invention Grant
- Patent Title: Compounds and methods for modulating angiotensinogen expression
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Application No.: US15763942Application Date: 2016-10-07
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Publication No.: US10912792B2Publication Date: 2021-02-09
- Inventor: Adam Mullick , Mark J. Graham , Punit P. Seth , Susan M. Freier
- Applicant: Ionis Pharmaceuticals, Inc.
- Applicant Address: US CA Carlsbad
- Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee: Ionis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Knobbe. Martens, Olson & Bear, LLP
- International Application: PCT/US2016/056068 WO 20161007
- International Announcement: WO2017/062816 WO 20170413
- Main IPC: A61K31/712
- IPC: A61K31/712 ; A61K31/7125 ; C07H21/00 ; C12N15/113 ; C07H21/02 ; C07H21/04 ; A61P9/12
Abstract:
Disclosed herein are compositions and compounds comprising modified oligonucleotides for modulating AGT and modulating a RAAS pathway related disease, disorder and/or condition in an individual in need thereof. A RAAS pathway related disease, disorder and/or condition in an individual such as hypertension can be treated, ameliorated, delayed or prevented with the administration of antisense compounds targeted to AGT.
Public/Granted literature
- US20190160090A1 COMPOUNDS AND METHODS FOR MODULATING ANGIOTENSINOGEN EXPRESSION Public/Granted day:2019-05-30
Information query
