Invention Grant
- Patent Title: Tumor infiltrating lymphocytes and methods of therapy
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Application No.: US15947688Application Date: 2018-04-06
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Publication No.: US10912797B2Publication Date: 2021-02-09
- Inventor: Branden Moriarity , Beau Webber , Modassir Choudhry , Steven A. Rosenberg , Douglas C. Palmer , Nicholas P. Restifo
- Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA , INTIMA BIOSCIENCE, INC. , The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Applicant Address: US MN Minneapolis; US NY New York; US MD Bethesda
- Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA,INTIMA BIOSCIENCE, INC.,The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Current Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA,INTIMA BIOSCIENCE, INC.,The United States of America, as Represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MN Minneapolis; US NY New York; US MD Bethesda
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K35/17
- IPC: A61K35/17 ; C12N15/113 ; C07K14/705 ; C07K14/47 ; A61P31/00 ; A61P35/00 ; A61K9/00 ; C07K14/725 ; C07K14/715 ; C12N5/0783 ; C12N9/22 ; C12N15/79 ; C12N15/90 ; A61K45/06
Abstract:
Genetically modified compositions, such as non-viral vectors and tumor infiltrating lymphocytes, for the treatment of gastrointestinal cancer are disclosed. Disclosed are methods of utilizing a CRISPR system to generate genetically modified compositions. Also disclosed are the methods of making and using the genetically modified compositions for the treatment of gastrointestinal cancer.
Public/Granted literature
- US20190008899A1 TUMOR INFILTRATING LYMPHOCYTES AND METHODS OF THERAPY Public/Granted day:2019-01-10
Information query
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