- Patent Title: Oxadiazolones as transient receptor potential channel inhibitors
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Application No.: US16421114Application Date: 2019-05-23
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Publication No.: US10913742B2Publication Date: 2021-02-09
- Inventor: Huifen Chen , Daniel Shore , Elisia Villemure , Matthew Volgraf , Baihua Hu , Aijun Lu , Andrew Cridland , Stuart Ward , Francis Beaumier , Martin Dery , Robin Larouche-Gauthier
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Robert C. Hall
- Priority: CN201711122317 20171114
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D473/30 ; C07D471/04 ; C07D513/04 ; A61K31/519 ; A61P11/06 ; C07D498/04
Abstract:
The invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as respiratory disorders or pain.
Public/Granted literature
- US20190284189A1 OXADIAZOLONES AS TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS Public/Granted day:2019-09-19
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