Invention Grant
- Patent Title: RAGE fusion proteins with improved stability and ligand binding affinity and uses thereof
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Application No.: US16571011Application Date: 2019-09-13
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Publication No.: US10913784B2Publication Date: 2021-02-09
- Inventor: Robert Hughes , William Strohl
- Applicant: BioAge Labs, Inc.
- Applicant Address: US CA Richmond
- Assignee: BioAge Labs, Inc.
- Current Assignee: BioAge Labs, Inc.
- Current Assignee Address: US CA Richmond
- Agency: Fenwick & West LLP
- Agent Payal Sud
- Main IPC: C07K14/705
- IPC: C07K14/705
Abstract:
The present invention provides soluble RAGE-Fc fusion proteins with increased stability and extended half-life capable of binding endogenous RAGE ligands with high apparent affinity. The present invention also provides methods of making and using stable, soluble RAGE-Fc fusion proteins. These soluble RAGE-Fc fusion proteins are useful as therapeutics based on their ability to bind endogenous RAGE ligands.
Information query
