Invention Grant
- Patent Title: Yeast strain with xylose utilizing capacity
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Application No.: US16204020Application Date: 2018-11-29
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Publication No.: US10913942B2Publication Date: 2021-02-09
- Inventor: Sun Mi Lee , Sangdo Yook , Youngsoon Um , Gyeongtaek Gong , Jiwon Kim
- Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Seoul
- Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Seoul
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: KR10-2018-0117860 20181002
- Main IPC: C12N9/92
- IPC: C12N9/92 ; C12N1/16 ; C12P7/64 ; C12N9/12 ; C12N15/01 ; C12N15/52 ; C07K14/39

Abstract:
Disclosed herein are a yeast strain capable of utilizing xylose as a carbon source and a method for producing lipids using the same. The yeast strain is obtained by adaptively evolving a wild-type yeast strain which cannot utilize xylose as a carbon source so that it can produce high density lipids and then transforming the adaptively evolved strain to obtain the ability to metabolize xylose. Since the strain does not have the xylose metabolic pathway based on oxidoreductase, it can produce biodiesel and biomaterials based on lipid and lignocellulosic biomass at a high yield without a problem of cofactor imbalance and can greatly improve the economic feasibility and sustainability of the production processes of biodiesel and biomaterials.
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