A display substrate includes: a display region having an irregular edge portion; and a light-shielding area located around the display region; wherein: a pixel array is disposed in the display region; the pixel array includes outermost edge pixels of the irregular edge portion, and central pixel; each of the edge pixels includes at least one edge sub-pixel; each of the edge sub-pixels includes a light-shielding sub-region and a light-emitting sub-region arranged along a row direction; and the light-shielding sub-region is located at a side of each of the edge sub-pixels proximal to the light-shielding region.