Systems and methods for providing audio streams over peripheral component interconnect (PCI) express (PCIE) links are disclosed. In particular, exemplary aspects of the present disclosure are used to calculate an uplink timing requirement and adjust a margin time before a modem encodes audio data so that the encoding is done before data is transmitted to an external network. Further aspects of the present disclosure allow a first integrated circuit (IC) to synchronize its clock with that of the modem.