Provided herein are method and device for configuring and acquiring transmission parameters of physical layer, the method comprising: dividing transmission resources into N resource groups, where N is greater than or equal to 1; determining first type of transmission parameter of the physical layer, the first type of transmission parameter of the physical layer comprises at least one of: indication information on definitions of basic resource units, indication information on aggregation of time interval units of physical layers, information on parameter configuration of basic transmission structures, information on numerology parameter configuration, indication information on mapping of channel or signals, indication information on resource allocation methods, indication information on available bandwidths in frequency domain of resource groups, indication information on transmission powers of resources, and configuration information of measurement pilots; notifying receiving terminal of the first type of transmission parameters of the physical layer corresponding to the N resource groups.