An electronic device and method for taking a picture using the electronic device are provided. The electronic device includes a housing, a display screen mounted on the housing, and a camera. The display screen includes a first display region and a second display region. The first display region has a pixel density less than that of the second display region. The camera includes a lens facing toward the first display region. At least a part of the camera is movable, such that the lens of the camera is movable in a plane parallel to the first display region. The lens is configured to take at least two initial pictures at positions in the first display region that are different from each other. A target picture free from pixels of the first display region is synthesized based on the at least two initial pictures.