The present invention relates to the field of intelligent machining, in particular to a parallel control method based on multi-period differential sampling and digital twinning technologies, the method comprising the following steps of: a. detecting machining conditions of dotting machine equipment by using a multi-period differential sampling technology; b. establishing a digital twinning control model; and c. controlling a simulation model of the dotting machine equipment according to a detection judgment result so as to perform parallel control on the dotting machine equipment. According to the parallel control method based on multi-period differential sampling and digital twinning modelling provided by the present invention, for the digital twinning model of the dotting machine equipment, the parallel control method establishes a simulation model and a detection model of the dotting machine equipment by using a virtual-real synchronization technology; simulation dotting machine equipment operates in synchronization with the physical dotting machine equipment.