A configuration manager is associated with a Networked Control System (NCS) comprising a plurality of sensors and actuators. The configuration manager automatically discovers the hardware and/or software configurations of the sensors and actuators, and analyzes that information in order to detect whether any of the sensors and actuators have been tampered with. Provided the configuration manager detects such tampering, the configuration manager indicates the tampering to a control manager of the NCS, which then functions to minimize potential damage to the NCS.