Invention Grant
- Patent Title: Benzothiazole derivatives as DYRK1 inhibitors
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Application No.: US16341630Application Date: 2017-10-12
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Publication No.: US10927106B2Publication Date: 2021-02-23
- Inventor: John Sigurd Svendsen , Wenche Stensen , Roderick Alan Porter
- Applicant: PHARMASUM THERAPEUTICS AS
- Applicant Address: NO Kvaløysletta
- Assignee: PHARMASUM THERAPEUTICS AS
- Current Assignee: PHARMASUM THERAPEUTICS AS
- Current Assignee Address: NO Kvaløysletta
- Agency: Fox Rothschild LLP
- Priority: GB1617339 20171012
- International Application: PCT/EP2017/076118 WO 20171012
- International Announcement: WO2018/069468 WO 20180419
- Main IPC: C07D417/04
- IPC: C07D417/04 ; C07D513/04 ; C07D417/14

Abstract:
The present invention relates to compounds of Formula (I), which are DYRK1A and/or DYRK1B inhibitors, and their use in the treatment of neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD), metabolic disorders such as Metabolic Syndrome or diabetes mellitus, and cancer.
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