Invention Grant
- Patent Title: B cell maturation antigen binding proteins
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Application No.: US16159545Application Date: 2018-10-12
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Publication No.: US10927180B2Publication Date: 2021-02-23
- Inventor: Holger Wesche , Bryan D. Lemon , Richard J. Austin
- Applicant: HARPOON THERAPEUTICS, INC.
- Applicant Address: US CA South San Francisco
- Assignee: HARPOON THERAPEUTICS, INC.
- Current Assignee: HARPOON THERAPEUTICS, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P35/00 ; A61P35/04 ; A61P35/02 ; A61K47/68 ; C07K16/18 ; A61K39/00

Abstract:
Disclosed herein are B cell maturation antigen binding proteins with improved binding affinities and improved ability to mediate killing of cancer cells expressing B cell maturation antigen (BCMA). Pharmaceutical compositions comprising the binding proteins disclosed herein and methods of treatment of a cancer or a metastasis thereof using such formulations are further provided.
Public/Granted literature
- US20190135930A1 B CELL MATURATION ANTIGEN BINDING PROTEINS Public/Granted day:2019-05-09
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