Invention Grant
- Patent Title: Copolymer and application therefor
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Application No.: US16313292Application Date: 2017-06-28
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Publication No.: US10927206B2Publication Date: 2021-02-23
- Inventor: Kazuhiko Ishihara , Masaru Matsuda , Tomozumi Noda , Satoshi Yamada , Nobuyuki Sakamoto
- Applicant: NOF CORPORATION , THE UNIVERSITY OF TOKYO
- Applicant Address: JP Tokyo; JP Tokyo
- Assignee: NOF CORPORATION,THE UNIVERSITY OF TOKYO
- Current Assignee: NOF CORPORATION,THE UNIVERSITY OF TOKYO
- Current Assignee Address: JP Tokyo; JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2016-129411 20160629
- International Application: PCT/JP2017/023654 WO 20170628
- International Announcement: WO2018/003821 WO 20180104
- Main IPC: C08F230/02
- IPC: C08F230/02 ; C08F212/08 ; C08F220/18 ; C08J3/28 ; A61L27/34 ; A61L33/06 ; C08J3/24 ; C09D143/02 ; C08J7/04 ; C08F12/22 ; C08F12/26

Abstract:
Provided are a copolymer having biocompatibility sufficient for use in medical material applications, and a method of forming a crosslinked body, the method including imparting biocompatibility to a substrate surface through the use of the copolymer. More specifically, a protein adsorption-suppressing effect and a cell adhesion-suppressing effect, which are features of a phosphorylcholine group, are imparted to the substrate surface. It has been found that a copolymer containing a phosphorylcholine constitutional unit and a photoreactive constitutional unit, or a copolymer containing a phosphorylcholine constitutional unit, a photoreactive constitutional unit, and a hydrophobic constitutional unit can impart a protein adsorption-suppressing effect and a cell adhesion-suppressing effect to a substrate surface through a simple approach called photoirradiation.
Public/Granted literature
- US20190153137A1 COPOLYMER AND APPLICATION THEREFOR Public/Granted day:2019-05-23
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