Invention Grant
- Patent Title: Oligonucleotides comprising modified nucleosides
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Application No.: US16307520Application Date: 2017-06-30
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Publication No.: US10927380B2Publication Date: 2021-02-23
- Inventor: Jeff Carter , Bharat Gawande , Nebojsa Janjic , Daniel Schneider
- Applicant: SOMALOGIC, INC.
- Applicant Address: US CO Boulder
- Assignee: SOMALOGIC, INC.
- Current Assignee: SOMALOGIC, INC.
- Current Assignee Address: US CO Boulder
- Agency: McNeill Baur PLLC
- International Application: PCT/US2017/040299 WO 20170630
- International Announcement: WO2018/005974 WO 20180104
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/115 ; C12N15/11 ; C12N15/10 ; C12Q1/6876
Abstract:
Polynucleotides, such as aptamers, comprising at least first one 5-position modified pyrimidine and at least one second 5-position modified pyrimidine are provided, wherein the first and second 5-position modified pyrimidines are different. Methods of selecting and using such polynucleotides, such as aptamers, are also provided.
Public/Granted literature
- US20190177730A1 Oligonucleotides Comprising Modified Nucleosides Public/Granted day:2019-06-13
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