Invention Grant
- Patent Title: Compositions and methods for identification, assessment, prevention, and treatment of T-cell exhaustion using CD39 biomarkers and modulators
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Application No.: US15518860Application Date: 2015-10-16
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Publication No.: US10927410B2Publication Date: 2021-02-23
- Inventor: William N. Haining , Arlene H. Sharpe , Jernej Godec
- Applicant: Dana-Farber Cancer Institute, Inc. , President and Fellows of Harvard College
- Applicant Address: US MA Boston; US MA Cambridge
- Assignee: Dana-Farber Cancer Institute, Inc.,President and Fellows of Harvard College
- Current Assignee: Dana-Farber Cancer Institute, Inc.,President and Fellows of Harvard College
- Current Assignee Address: US MA Boston; US MA Cambridge
- Agency: Foley Hoag LLP
- International Application: PCT/US2015/055938 WO 20151016
- International Announcement: WO2016/061456 WO 20160421
- Main IPC: C12N5/02
- IPC: C12N5/02 ; C12Q1/6881 ; G01N33/569 ; C12Q1/6883

Abstract:
The present invention is based on the identification, of compositions and methods for the identification, assessment, prevention, and treatment of T-cell exhaustion using CD39 biomarkers and modulators.
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