Invention Grant
- Patent Title: Methods and compositions for prediction of therapeutic efficacy of cancer treatments and cancer prognosis
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Application No.: US15565306Application Date: 2016-04-13
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Publication No.: US10927413B2Publication Date: 2021-02-23
- Inventor: Ugur Sahin , Ozlem Tureci , Daniel Maurus
- Applicant: Ganymed Pharmaceuticals GmbH , TRON—Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg—Universitat Mainz gGmbH
- Applicant Address: DE Mainz; DE Mainz
- Assignee: Ganymed Pharmaceuticals GmbH,TRON—Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg—Universitat Mainz gGmbH
- Current Assignee: Ganymed Pharmaceuticals GmbH,TRON—Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg—Universitat Mainz gGmbH
- Current Assignee Address: DE Mainz; DE Mainz
- Agency: Neal, Gerber & Eisenberg LLP
- Agent Kevin A. O'Connor
- Priority: WOPCT/EP2015/058212 20150415
- International Application: PCT/EP2016/058061 WO 20160413
- International Announcement: WO2016/166124 WO 20161020
- Main IPC: C12Q1/6883
- IPC: C12Q1/6883 ; C12Q1/6886 ; A61K47/68 ; A61K39/395
Abstract:
The invention generally relates to methods and compositions for the prediction of therapeutic efficacy of cancer treatments and the prognosis of cancer. The invention discloses markers that are associated with favorable and unfavorable outcomes, respectively, in certain cancer treatments and are useful as prognostic markers for cancer. Methods involving these markers are disclosed for predicting cancer therapy benefit and prognosing clinical outcome for cancer patients.
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