A black matrix, a color filter and a method of preparing the same, a display panel, and a display device are provided, including: a plurality of first walls extending along a first direction; and a plurality of second walls extending along a second direction intersected with the plurality of first walls along the first direction at intersection regions, wherein the plurality of first walls and the plurality of second walls form a mesh-like structure with a plurality of openings. At least one of the intersection regions is to receive a main support column including a top end, and the at least one of the intersection regions to receive the main support column is widened to be larger than a dimension of the top end of the main support column to be received therein.