Provided are embodiments including a computer-implemented method, system and computer program product for determining precise operand-store-compare (OSC) predictions to avoid false dependencies. Some embodiments include detecting an instruction causing an OSC event, wherein the OSC event is at least one of a store-hit-load event or a load-hit-store event, marking an entry in a queue for the instruction based on the detected OSC event, wherein marking the entry comprises setting a bit and saving a tag in the entry in the queue. Some embodiments also include installing an address for the instruction and the tag in the history table responsive to completing the instruction.