The present invention provides an antenna module and a mobile terminal. The mobile terminal comprises a back cover, a main board, a plastic back shell, and a USB interface, the antenna module comprises a radiator structured on a surface of the plastic back shell facing the back cover and a feeding point and a grounding point disposed on the main board, the antenna module further comprises a matching network, a first tuning switch, a second tuning switch and a third tuning switch, the surface of the plastic back shell facing the back cover includes a first structuring region for structuring the radiator and a second region other than the first structuring region, the radiator completely covers the first structuring region, and the orthographic projections of the radiator and the USB interface on the main board do not overlap each other.