A surgical camera system is provided which includes a plurality of imaging devices each having a tunable iris configured to change between at least two different sized numerical apertures. A video stream is produced at a frame rate greater than or equal to about 20 frames per second from first and second images produced by respective sensors and tunable irises of at least two of the imaging devices, the tunable irises controlled to different numerical apertures, the first images acquired at a respective first numerical aperture of a first imaging device and the second images acquired at a respective second numerical aperture of a second imaging device, different from the respective first numerical aperture. The video stream alternates between the first images and the second images so that the video stream results in a three-dimensional effect at a display device when the video stream is rendered thereon.