Invention Grant
- Patent Title: VISTA antagonist and methods of use
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Application No.: US15111550Application Date: 2015-01-23
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Publication No.: US10933115B2Publication Date: 2021-03-02
- Inventor: Randolph J. Noelle , Sabrina Ceeraz , Isabelle Lemercier , Elizabeth Nowak , Janet Lines , Li Wang , Mark Spaller
- Applicant: King's College London , The Trustees of Dartmouth College
- Applicant Address: GB London; US NH Hanover
- Assignee: King's College London,The Trustees of Dartmouth College
- Current Assignee: King's College London,The Trustees of Dartmouth College
- Current Assignee Address: GB London; US NH Hanover
- Agency: Baker, Donelson, Bearman, Caldwell & Berkowitz, PC
- Agent Robin L. Teskin
- International Application: PCT/US2015/012752 WO 20150123
- International Announcement: WO2015/109340 WO 20150723
- Main IPC: C07K11/00
- IPC: C07K11/00 ; A61K38/10 ; C07K7/08 ; A61K45/06 ; A61K9/00 ; A61K39/00 ; C07K16/28 ; G01N33/566 ; A61K38/00
Abstract:
The present invention is directed to a peptide, multimer, conjugate, analog, derivative or mimetic thereof that inhibits the activity of VISTA. The invention further contemplates therapeutic use of the VISTA antagonist peptide, multimer, conjugate, derivative or mimetic thereof, including treating or preventing cancer, bacterial infections, viral infections, parasitic infections and fungal infections, as well as research uses of the antagonist.
Public/Granted literature
- US20160331803A1 VISTA ANTAGONIST AND METHODS OF USE Public/Granted day:2016-11-17
Information query
