Invention Grant
- Patent Title: Conjugated lipomers and uses thereof
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Application No.: US16181109Application Date: 2018-11-05
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Publication No.: US10933139B2Publication Date: 2021-03-02
- Inventor: James E. Dahlman , Avraham D. Schroeder , Daniel Griffith Anderson , Robert S. Langer , Christopher G. Levins
- Applicant: Massachusetts Institute of Technology
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technology
- Current Assignee: Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K47/22
- IPC: A61K47/22 ; A61K47/54 ; A61K47/59 ; A61K47/69 ; C07D257/02 ; C07D273/08 ; A61K9/00 ; A61K47/34 ; C08G73/10 ; A61K9/127 ; C07D273/00 ; C07D295/084 ; C12N15/113
Abstract:
The present invention provides inventive conjugated polyethyleneimine (PEI) polymers and conjugated aza-macrocycles (collectively referred to herein as “conjugated lipomers” or “lipomers”) containing one or more groups of the formula (iii): wherein R3 and R4 are as defined herein. Also provided are compositions comprising the inventive conjugated lipomers, and methods of preparation and use.
Public/Granted literature
- US20190167795A1 CONJUGATED LIPOMERS AND USES THEREOF Public/Granted day:2019-06-06
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