Invention Grant
- Patent Title: Reversible covalent linkage of functional molecules
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Application No.: US16714975Application Date: 2019-12-16
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Publication No.: US10933142B2Publication Date: 2021-03-02
- Inventor: Mark Smith , Stephen Caddick , James Baker , Vijay Chudasama
- Applicant: UCL BUSINESS LTD
- Applicant Address: GB London
- Assignee: UCL BUSINESS LTD
- Current Assignee: UCL BUSINESS LTD
- Current Assignee Address: GB London
- Agency: Dorf & Nelson LLP
- Agent Scott D. Locke, Esq.
- Priority: GB0913965 20090810,GB0913967 20090810,GB0914321 20090814
- Main IPC: A61P29/00
- IPC: A61P29/00 ; A61P31/04 ; A61P31/10 ; A61P31/12 ; A61P7/02 ; A61P11/00 ; A61P11/14 ; A61P25/00 ; A61P25/22 ; A61P25/08 ; A61P25/04 ; A61P25/24 ; A61P21/02 ; A61P1/08 ; A61P1/04 ; A61P23/02 ; A61P5/00 ; A61P35/00 ; A61P37/06 ; A61P37/04 ; A61K47/54 ; A61K47/62 ; A61K47/60 ; A61K9/12 ; C07D207/416 ; C07D207/456 ; C07D209/52 ; C07K14/655 ; C07K14/435 ; G01N33/58 ; A61K49/00 ; A61K47/55
Abstract:
The present invention relates to the use of a compound containing a moiety of formula (I) as a reagent for linking a compound of formula R1—H which comprises a first functional moiety of formula F1 to a second functional moiety of formula F2 wherein X, X′, Y, R1, F1 and F2 are as defined herein. The present invention also provides related processes and products. The present invention is useful for creating functional conjugate compounds, and specifically conjugates in which at least one of the constituent molecules carries a thiol group.
Information query
