An apparatus and a method for monitoring a tire pressure of a vehicle are provided. The apparatus for monitoring a tire pressure of a vehicle according to the present disclosure includes a first sensor configured for measuring a tire pressure of one of first to fourth wheels of the vehicle, a plurality of second sensors configured for respectively measuring wheel speeds of the first to fourth wheels, an analysis device configured for analyzing tire pressures of the first to fourth wheels based on a measured value from the first sensor and measured values from the second sensors, and a controller configured for determining a tire in a low-pressure state based on the tire pressure analysis results of the first to fourth wheels.