A tube cap (104) for a multi-chamber tube container (102) comprises a base plate (106) and a lid (120). The base plate is coupleable to the multi-chamber tube container and has an opening disposed therein, wherein the opening is positionable in communication with at least a first tube head (114) of a first tube (112) of the multi-chamber tube container. The lid is removably coupleable to the base plate and has both a pintle (122) extending from and a gasket (124) disposed on an inner surface thereof. When the lid and the base plate are coupled, the pintle extends into and seals a first orifice (108) disposed in the first tube head and the gasket is urged into sealing contact with a second orifice (110) disposed in a second tube head (118) of a second tube (116) of the multi-chamber tube container.