Invention Grant
- Patent Title: COMT inhibiting methods and compositions
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Application No.: US15779340Application Date: 2016-11-25
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Publication No.: US10934283B2Publication Date: 2021-03-02
- Inventor: James Barrow , Glen Ernst , Dominique Swinnen , Florian Montel , Sabine Defays , Yifang Huang , Pablo de León , Michael Steven Poslusney
- Applicant: LIEBER INSTITUTE FOR BRAIN DEVELOPMENT
- Applicant Address: US MD Baltimore
- Assignee: LIEBER INSTITUTE FOR BRAIN DEVELOPMENT
- Current Assignee: LIEBER INSTITUTE FOR BRAIN DEVELOPMENT
- Current Assignee Address: US MD Baltimore
- Agency: Ballard Spahr LLP
- International Application: PCT/US2016/063779 WO 20161125
- International Announcement: WO2017/091818 WO 20170601
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P25/00 ; A61K31/165 ; A61K31/197 ; A61K31/4985

Abstract:
Compounds that inhibit COMT enzyme and pharmaceutical compositions comprising the same are provided herein. Methods of treating various psychiatric and neurological disorders with the compounds and pharmaceutical compositions described herein are also provided.
Public/Granted literature
- US20180305354A1 COMT Inhibiting Methods and Compositions Public/Granted day:2018-10-25
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