Invention Grant
- Patent Title: Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors
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Application No.: US16517149Application Date: 2019-07-19
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Publication No.: US10934299B2Publication Date: 2021-03-02
- Inventor: Stephanos Ioannidis , Adam Charles Talbot , Bruce Follows , Alexandre Joseph Buckmelter , Minghua Wang , Ann-Marie Campbell , Darby Rye Schmidt , David Joseph Guerin , Justin Andrew Caravella , R. Bruce Diebold , Anna Ericsson , David R. Lancia, Jr.
- Applicant: Valo Early Discovery, Inc.
- Applicant Address: US MA Boston
- Assignee: Valo Early Discovery, Inc.
- Current Assignee: Valo Early Discovery, Inc.
- Current Assignee Address: US MA Boston
- Agency: Choate, Hall & Stewart LLP
- Agent Michael A. Shinall; Nicholas J. Pace
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D519/00 ; A61K31/519
Abstract:
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: where m, n, X1, X2, R1-R5, R5′ and R6 are described herein.
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