- Patent Title: Tricyclic heterocycle compounds useful as HIV integrase inhibitors
-
Application No.: US16465614Application Date: 2017-12-01
-
Publication No.: US10934312B2Publication Date: 2021-03-02
- Inventor: Thomas H. Graham , Tao Yu , Sherman T. Waddell , John A. McCauley
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; John C. Todaro
- International Application: PCT/US2017/064116 WO 20171201
- International Announcement: WO2018/102634 WO 20180607
- Main IPC: A61K31/53
- IPC: A61K31/53 ; A61P31/18 ; C07D471/16 ; C07D498/16 ; C07D491/22 ; A61K45/06
Abstract:
The present invention relates to Tricyclic Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts or prodrug thereof, wherein A, X, Y, Z, R1, R7A, R7B and R8 are as defined herein. The present invention also relates to compositions comprising at least one Tricyclic Heterocycle Compound, and methods of using the Tricyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.
Public/Granted literature
- US20200017524A1 TRICYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS Public/Granted day:2020-01-16
Information query
