Invention Grant
- Patent Title: Methods for increasing lean body mass with resistance training and a GDF8 inhibitor that is an anti-GDF8 antibody
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Application No.: US15099701Application Date: 2016-04-15
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Publication No.: US10934349B2Publication Date: 2021-03-02
- Inventor: Robert C. Pordy , Xiaobing Qian , Stephen Donahue
- Applicant: Regeneron Pharmaceuticals, Inc.
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Merchant & Gould, P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/22 ; C07K14/47 ; C07K14/475 ; A61K39/00

Abstract:
The disclosure provides compositions, kits, and methods of using a GDF-8 inhibitor to increase lean muscle mass. In embodiments, a GDF-8 inhibitor is an antibody or antigen binding fragment thereof that specifically binds GDF-8. In embodiments, a method comprises providing an exercise regimen for the subject, and administering a composition comprising an effective amount of a GDF-8 inhibitor.
Public/Granted literature
- US20160304595A1 METHODS OF INCREASING STRENGTH AND FUNCTIONALITY WITH GDF8 INHIBITORS Public/Granted day:2016-10-20
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