A blockchain-based software compliance system includes a computing system with a first computing device associated with first software. A monitoring system detects an update of the first computing device to replace the first software with second software, and generates a blockchain transaction that is directed to a blockchain address and that identifies the replacement of the first software with the second software. The monitoring system broadcasts the blockchain transaction, which is received by a blockchain device that executes a smart contract associated with the blockchain address. The blockchain device then determines that the execution of the smart contract has provided an indication that the updating of the first computing device with the second software does not comply with a computing system software matrix and, in response, causes an update to the first computing device that replaces the second software with third software that complies with the computing system software matrix.