- Patent Title: Method for characterizing the physiological state of a patient from the analysis of the cerebral electrical activity of said patient, and monitoring device applying said method
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Application No.: US14398217Application Date: 2013-05-03
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Publication No.: US10939838B2Publication Date: 2021-03-09
- Inventor: Thomas Similowski , Mathieu Raux , Mario Chavez , Jacques Martinerie , Pierre Pouget
- Applicant: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , FONDATION ICM—INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE , ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
- Applicant Address: FR Paris; FR Paris; FR Paris; FR Paris; FR Paris
- Assignee: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6),CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,FONDATION ICM—INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE,ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
- Current Assignee: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6),CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,FONDATION ICM—INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE,INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE,ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
- Current Assignee Address: FR Paris; FR Paris; FR Paris; FR Paris; FR Paris
- Agency: Sughrue Mion, PLLC
- Priority: FR1254089 20120503
- International Application: PCT/EP2013/059279 WO 20130503
- International Announcement: WO2013/164462 WO 20131107
- Main IPC: A61B5/04
- IPC: A61B5/04 ; A61B5/048 ; A61B5/00 ; A61M16/00

Abstract:
The invention relates to a method for detecting a physiological state of a patient deviating from a reference physiological state, in which, after having determined, in each of Q frequency bands, R reference matrices PRq,r with qe[1 . . . Q] and rϵ[1 . . . R] which correspond to the reference physiological state, the following steps are repeated in a loop: carrying out measurements, in M time segments, of an electroencephalographic signal; filtering and centering the measurements in Q frequency bands to obtain and determine M×Q scaled matrices of spatial covariance; for each time segment m, calculating a deviation from the reference physiological state, and comparing each of the deviations from the reference physiological state to a predefined threshold. The invention also relates to a monitoring device applying said method.
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