Disclosed is a minimally invasive instrument with instant force feedback function, including a minimally invasive device, a sensing device, a computing device, and a warning device. The minimally invasive device may have an invasive portion, which may enter the human body to perform surgical operations. The sensing device is provided on the invasive portion of the minimally invasive device and may include a flexible conductive film, a plurality of bionic films and a plurality of liquid beads. The plurality of bionic films may be provided on a flexible conductive film. Each of the plurality of liquid beads may be covered by each of the plurality of bionic films. The computing device may be electrically connected to the flexible conductive film. The warning device may receive a warning signal and generate a warning message.