A ball-type anti-reflux biliary stent, including a meshed body, a cup and a ball. The cup and the ball are respectively provided at two ends of the meshed body. Inner diameters of the cup and the ball is larger than that of the meshed body. The meshed body includes a plurality of sections, and two adjacent sections are connected by a flexible wire. The cup of the stent is a cylinder open outwards, and the opening of the ball is connected to a tube having a substantially elliptical cross section. Therefore, a displacement of the stent is prevented for an accurate fixation of the stent. Moreover, the intestinal juice is prevented from flowing back into the biliary tract, avoiding infectious diseases.