Apparatus and methods related to fire suppression in cargo compartments of aircraft are disclosed. An exemplary apparatus provides an interface (38) between a fire suppressant conduit (18) and a cargo panel (28) of a cargo compartment (12) of an aircraft (10). The apparatus comprises an adaptor (40) configured to provide the fire suppressant conduit (18) access to the cargo compartment (12) through the cargo panel (28) and a sealing member (42) configured to provide a seal between the adaptor (40) and the fire suppressant conduit (18). The adaptor (40) comprises an aperture (56) for receiving the fire suppressant conduit (18) where the aperture (56) is sized to permit passage of a nozzle (36) of the fire suppressant conduit (18) therethrough. Associated methods (600, 700) for removing the cargo panel (28) of the cargo compartment (12) of the aircraft (10) without disassembly of the nozzle (36) of the fire suppressant conduit (18) are also disclosed.